Accurate, high-resolution cellular profiling — at the click of a button.
iSort™ is a robust, AI-powered digital cytometry platform for quantifying cell type composition and gene expression.
Accurate cell type proportions in minutes.
Starting with bulk gene expression data from blood or tissue samples, iSort™ Fractions provides quantified cell composition for each sample — at the click of a button.
iSort™ boasts proven accuracy across sample types, library preparation kits, and RNA-seq methods, with even greater accuracy when paired with Agilent SureSelect targeted sequencing kits.
The first AI powered tool for inferring cell-type-specific gene expression.
Using grouped cell proportion data from iSort™ Fractions, iSort™ HiRes infers cell-type-specific gene expression.
Built on iSort’s powerful digital cytometry platform, HiRes provides an even deeper level of insight into immune cell makeup - and opens up a vast array of possibilities across life sciences research.
Expert-led Data Science Services tailored to your goals.
From consultation and planning to post analysis, reporting, and discussions — our end-to-end data science services are provided by a seasoned team of experts.
A collaborative approach ensures we support your goals whether that's custom signature matrices for tissues or species of interest, modeling for biomarker discovery, clinical outcome analysis, or other outcomes.
- Start-to-end data processing - from data QC to analysis summary
- Map and quantify RNA-seq reads, perform RNA-seq data QC
- Run iSort™ Fractions
- Run iSort™ HiRes
- Create a custom signature matrix
- Post data analysis tailored to your goals
iSort™ Fractions
Single-Cell
RNA Seq
Flow Cytometry /
CyTOF
IHC
A simple workflow backed by a powerful AI platform.
Starting from bulk tissue and blood gene expression data, iSort’s powerful AI-driven model quantifies cell-type specific composition and gene expression.
Sample & Library Prep
iSort™ is robust to sample and library preparation methods. No tissue dissociation required. Users may also start with an existing bulk RNA expression profile.
Bulk RNA Expression Profile
iSort™ is robust to RNA-seq platforms and alignment methods. 1,2
Run iSort™
iSort™ Fractions
Quantifies cellular composition from bulk expression data, using a predefined blood or tissue signature matrix.
iSort™ HiRes
Infers cell-type-specific gene expression from bulk expression data. Requires results from iSort™ Fractions.
Post Analysis
CiberMed can conduct post-analysis on the iSort™ output through data science services, or the client may analyze the output themselves.
Boost accuracy with Agilent SureSelect technology.
Agilent SureSelect targeted sequencing panels — developed specifically for iSort™ Fractions blood and tissue modes — enable a combined SureSelect and iSort™ workflow for cellular profiling from bulk RNA-Seq data with enhanced sensitivity, accuracy, and robustness.
Our two flagship products — iSort™ Fractions and iSort™ HiRes — can be purchased as software as a service, or included as part of a collaborative data science services engagement tailored to support your goals.
- Determining cell type abundance and expression from bulk tissues with digital cytometry, Newman, A. M. et al. Nature Biotechnology 37, 773-782 (2019)
- Additional data on file.